Chelveston Aerodrome was originally opened in August 1941 by the Air Ministry for use as a wartime RAF base. The site was large enough to accommodate three runways, which were laid out in the then standard RAF triangular format. However, RAF Chelveston, known as Station 105, was used by the American Army Air Force (USAAF) from 6th December 1942 until 25th July 1945, for bomber operations over German occupied Europe. The airfield was in use by the 301st and then the 305th Bombardment Groups who flew the four engine Boeing B-17 Flying Fortress heavy bomber
At the end of hostilities, the airfield was briefly used as a satellite station for the 25 Maintenance Unit (MU).